Genebyond is seeking a highly motivated and creative scientists (Senior Scientist / Scientist/ Associate Scientist) with extensive experience in cell biology and protein engineering to join us participating in biotherapeutic discovery and development. The successful candidate will have demonstrated in-depth knowledge of molecular and cellular biology and ability to execute high quality creative scientific work independently and collaboratively.
1. Research Scientist-Protein and Antibody Engineering
Responsibilities:
- Responsible for molecular cloning, protein and antibody expression in various systems including bacterial and mammalian cells, purification and characterization
- Responsible for cell culture, chemical and cell-based assays, fluorescence-activated cell sorting (FACS), DNA library construction and screening.
- Participate in antibody generation, optimization and characterization.
- Provide critical lab support and collaboration in a fast paced, highly collaborative, dynamic and cross-functional work environment to advance company goals.
- Maintain a lab notebook and contribute to support documentation.
Requirements:
- PhD/MS/BS in Molecular Biology, Biochemical Engineering, Biochemistry or related discipline with 2-5-year academic or industrial experience.
- The ideal candidate will have a deep understanding and experience with early-stage drug discovery as it pertains to protein and antibody-based biotherapeutics
- Proficiency with vector design, molecular cloning, protein expression with E. coli, mammalian cell systems (HEK293, CHO)
- Proficiency with AKTA protein purification with affinity chromatography, IEX, SEC, etc.
- Hands on in homology modeling, surface plasmon resonance (SPR), flow cytometry FACS, SDS-PAGE, ELISA, microscopy are required, HPLC is a plus.
- Familiarity with antibody immunoassay and functional assay development
- Backgrounds in oncology, immunology and cell biology are preferred.
- Must be able to perform daily functions independently with little to no instructions on routine work, and with general instructions on new assignments.
- The successful candidate will be self-motivated, resourceful, and flexible with the ability to handle rapidly changing objectives and timelines.
- Extremely detail-oriented and diligent in experimental design, data analysis and review
- Excellent written and verbal communication skills
Contact email: HR at genebeyond.com
2. Research Scientist-Cell Biology
Responsibilities:
- Conduct experiment design, mammalian cell culture, transfection, molecular cloning, protein expression, molecular biology, cell signaling, flow cytometry, western blot, ELISA, etc.
- Implement biochemical and cellular functional assays (flow cytometry, immune cell quantification, PBMC stimulation and coculture assays, etc.) to support biotherapeutic discovery and development.
Requirements:
- PhD in Cell Biology, or other relevant biological science, with 2+ years of experience preferred; MS/BS with 3-5+ years of experience considered.
- Hands-on expertise with multiparametric flow cytometry, primary cells and/or immune cell experience is highly preferred.
- Strong teamwork, communication, and time management skills
Contact email: HR at genebeyond.com